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Zur Pathogenese des Urämiesyndroms. Brenztraubensäure, Acetoin und 2,3-Butylenglykol in Blut von Patienten mit Nieren- und Leberkrankheiten

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Summary

Acetoin and 2, 3-butylene glycol in blood of renal and hepatic patients are raised, when consciousness is disturbed. There is no correlation between blood levels of acetoin and 2, 3-butylene glycol and the degree of impairment of consciousness. Simultaneous determinations of acetoin and 2, 3-butylene glycol in blood and cerebrospinal fluid show that alterations of the cerebral pyruvic acid metabolism are difficult to detect in circulating blood.

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Literatur

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Authors and Affiliations

  1. Medizinische Universitätsklinik, Basel, Schweiz

    H. Thölen, F. Bigler, A. Heusler, W. Stauffacher & H. Staub

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  1. H. Thölen
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  2. F. Bigler
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  3. A. Heusler
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  4. W. Stauffacher
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  5. H. Staub
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Additional information

Mit Unterstützung des «Schweizerischen Nationalfonds» und der Firma F. Hoffmann-La Roche & Co., AG, Basel.

5. Mitteilung. — 1. Mitt.:H. Thölen, F. Bigler undH. Staub, Path. Microbiol.24, 262 (1961). — 2. Mitt.:F. Bigler, H. Thölen undH. Staub, Helv. physiol. Acta19, C11 (1961). — 3. Mitt.:H. Thölen, F. Bigler undH. Staub, Exper.17, 359 (1961). — 4. Mitt.:F. Bigler, H. Thölen undH. Staub, Schweiz. med. Wschr.91, 1259 (1961).

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Thölen, H., Bigler, F., Heusler, A. et al. Zur Pathogenese des Urämiesyndroms. Brenztraubensäure, Acetoin und 2,3-Butylenglykol in Blut von Patienten mit Nieren- und Leberkrankheiten. Experientia 18, 454–455 (1962). https://doi.org/10.1007/BF02175855

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  • DOI: https://doi.org/10.1007/BF02175855

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