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Decrease in the sympatho-inhibitory action of clonidine after destruction of the sympatho-inhibitory area

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Résumé

La destruction extensive de l'aire dépressive bulbaire provoque chez le chat une chute de la pression artérielle, du rythme cardiaque et une diminution de l'activité électrique du nerf splanchnique. La clonidine ne provoque alors qu'une augmentation de la pression artérielle, sans hypotension secondaire, ni diminution des potentiels splanchniques. La perte des influences sympatho-inhibitrices de la clonidine est encore plus nette chez le chien, car la destruction extensive de cette aire ne provoque qu'une diminution légère de la pression artérielle et de l'activité électrique du nerf splanchnique.

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Authors and Affiliations

  1. Faculté de Médecine Paris, Broussais Hôtel Dieu, 15, rue de l'Ecole de Médecine, F-75, Paris 6ème, France

    H. Schmitt, Hélène Schmitt & Simone Fénard

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  1. H. Schmitt
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  2. Hélène Schmitt
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  3. Simone Fénard
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Schmitt, H., Schmitt, H. & Fénard, S. Decrease in the sympatho-inhibitory action of clonidine after destruction of the sympatho-inhibitory area. Experientia 29, 1247–1249 (1973). https://doi.org/10.1007/BF01935099

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