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Effect of albumin on uncoupling of oxidative phosphorylation by chinoform in rat liver mitochondria

  • Pharmacologica
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Summary

Addition of serum albumin diminished the uncoupling effect of chinoform on oxidative phosphorylation in rat liver mitochondria. Upon increasing the concentration of magnesium ions in the medium, the action of serum albumin was diminished. These results indicate that serum albumin combines with chinoform in competition with magnesium ions.

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Authors and Affiliations

  1. Institute of Biochemistry, Faculty of Medicine, University of Nagoya, 466, Nagoya, (Japan)

    M. Hagihara & K. Yagi

Authors
  1. M. Hagihara
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  2. K. Yagi
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Hagihara, M., Yagi, K. Effect of albumin on uncoupling of oxidative phosphorylation by chinoform in rat liver mitochondria. Experientia 31, 1069–1070 (1975). https://doi.org/10.1007/BF02326965

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  • DOI: https://doi.org/10.1007/BF02326965

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