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The effect of combined chronic hypoxia and N-ethyl-N-nitrosourea on the carotid bodies of rats

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Summary

We measured the carotid body volume of rats treated with chronic hypoxia alone and chronic hypoxia together with a single neonatal injection of N-ethyl-N-nitrosourea (10 mg/kg). All the animals so treated showed enlargement of their carotid bodies, but no carotid body chemodectomas occurred.

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Literatur

  1. J. Arias-Stella, Am. J. Path.55, 82a (1969).

    Google Scholar 

  2. C. Edwards, D. Heath, P. Harris, Y. Castillo, H. Krüger andJ. Arias-Stella, J. Path.104, 231 (1971).

    Article  CAS  PubMed  Google Scholar 

  3. P. Landler andJ. M. Kay, Am. J. Path.79, 311 (1975).

    Google Scholar 

  4. M. J. Saldaña, L. E. Salem andR. Travezan, Human Path.4, 251 (1973).

    Article  Google Scholar 

  5. A. G. E. Pearse, J. M. Polak, F. W. D. Rost, J. Fontaine, C. Le Lièvre andN. Le Douarin, Histochemie34, 191 (1973).

    Article  CAS  PubMed  Google Scholar 

  6. P. Laidler andJ. M. Kay, J. Path.117, 183 (1975).

    Article  CAS  PubMed  Google Scholar 

  7. W. F. Mackenzie andF. M. Garner, J. natn. Cancer Inst.50, 1243 (1973).

    Article  CAS  Google Scholar 

  8. G. S. Trevino andW. B. Nessmith, Veterin. Path.9, 243 (1972).

    Article  CAS  Google Scholar 

  9. K. V. Jubb andP. C. Kennedy, Cancer10, 89 (1957).

    Article  CAS  PubMed  Google Scholar 

  10. C. D. Buergelt andK. M. Das, Pathologia vet.5, 84 (1968).

    Article  CAS  Google Scholar 

  11. C. Lombard andJ. Sarrazy, Bull. Acad. Vét. Fr.38, 209 (1965).

    Article  CAS  PubMed  Google Scholar 

  12. W. A. D. Anderson,Pathology, 4th edn. (C. V. Mosby, St. Louis 1966).

    Google Scholar 

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This work was supported by a grant from the North West Cancer Research Fund.

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Laidler, P., Kay, J.M. The effect of combined chronic hypoxia and N-ethyl-N-nitrosourea on the carotid bodies of rats. Experientia 32, 899–900 (1976). https://doi.org/10.1007/BF02003755

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  • DOI: https://doi.org/10.1007/BF02003755

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