Summary
We measured the carotid body volume of rats treated with chronic hypoxia alone and chronic hypoxia together with a single neonatal injection of N-ethyl-N-nitrosourea (10 mg/kg). All the animals so treated showed enlargement of their carotid bodies, but no carotid body chemodectomas occurred.
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This work was supported by a grant from the North West Cancer Research Fund.
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Laidler, P., Kay, J.M. The effect of combined chronic hypoxia and N-ethyl-N-nitrosourea on the carotid bodies of rats. Experientia 32, 899–900 (1976). https://doi.org/10.1007/BF02003755
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DOI: https://doi.org/10.1007/BF02003755