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Prostaglandin A2 (PGA2) increases the coronary vascular resistance in the guinea-pig isolated heart preparation

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Summary

Prostaglandin A2 (PGA2) in concentrations of 1.5·10−8 to 3·10−6 M was found to produce concentration-dependent increase in the coronary vascular resistance of the guinea-pig isolated heart without alterations in myocardial contractile force and oxygen consumption.

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Authors and Affiliations

  1. Pharmakologisches Institut der Universität Mainz, Obere Zahlbacher Strasse 67, D-6500, Mainz, Germany

    K. Schrör & R. Krebs

Authors
  1. K. Schrör
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  2. R. Krebs
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Supported by the Deutsche Forschungsgemeinschaft.

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Schrör, K., Krebs, R. Prostaglandin A2 (PGA2) increases the coronary vascular resistance in the guinea-pig isolated heart preparation. Experientia 33, 349–350 (1977). https://doi.org/10.1007/BF02002821

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