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Synthetic identification as a hexapeptide ofα substance-IB inducing sexual agglutination in Saccharomyces cerevisiae

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  • Chimica, Biochimica
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Summary

For the identification of a peptidyl principle inducing sexual agglutination in the yeast, 2 supposed hexapeptides (1a, b) were synthesized by the conventional method. The1a (H-Arg-Gly-Pro-Phe-Pro-Ile-OH) revealed complete identity with the natural peptide in TLC, MS and biological property on agglutination. The1b showed the sexual agglutinability in the same degree as1a, though distinct differences were observed in the chemical data. Both1a and1b had a strong bitter taste.

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References

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Author notes

  1. H. Aoyagi & N. Izumiya

    Present address: Laboratory of Biochemistry, Faculty of Science, Kyushu University, Higashi-ku, 812, Fukuoka, Japan

  2. A. Sakurai, K. Sakata & S. Tamura

    Present address: The Institute of Physical and Chemical Research, 351, Wako-shi, Saitama-ken, Japan

Authors and Affiliations

  1. Laboratory of Biochemistry, Faculty of Science, Kyushu University, Higashi-ku, 812, Fukuoka, Japan

    A. Sakurai, K. Sakata & S. Tamura

  2. The Institute of Physical and Chemical Research, 351, Wako-shi, Saitama-ken, Japan

    H. Aoyagi & N. Izumiya

Authors
  1. H. Aoyagi
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  2. N. Izumiya
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  3. A. Sakurai
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  4. K. Sakata
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  5. S. Tamura
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Aoyagi, H., Izumiya, N., Sakurai, A. et al. Synthetic identification as a hexapeptide ofα substance-IB inducing sexual agglutination in Saccharomyces cerevisiae. Experientia 33, 870–871 (1977). https://doi.org/10.1007/BF01951251

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  • DOI: https://doi.org/10.1007/BF01951251

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