Skip to main content
SpringerLink
Log in

Biotin as a regulator of some haematic parameters and of DNA-content of the liver of old rats

  • Published:
Experientia Aims and scope Submit manuscript

Summary

Biotin administration to old rats (28 months) causes in the blood an increase of ATP, glucose, triglycerides, alkaline phosphatase and a decrease of cholesterol and acid phosphatase; in the liver DNA and electrostatic interactions between DNA and histones are increased. Such parameters come within the values shown by adult rats.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. V. V. Frol'kis, L. N. Bogatskaya and E. V. Epshtein, Biokhim. Zh.38, 514 (1966).

    CAS  Google Scholar 

  2. D. Amici, G. L. Gianfranceschi, G. Marsili and L. Michetti, Experientia30, 633 (1974).

    Article  CAS  PubMed  Google Scholar 

  3. T. De Leo and L. Foti, Ricerca scient.30, 1696 (1960).

    Google Scholar 

  4. T. F. Zucker and M. Zucker, J. Nutr.80, 20 (1963).

    CAS  PubMed  Google Scholar 

  5. K. Salatka, D. Kresge, L. Harris, Jr., D. Edelstein and P. Ove, Exp. Geront.6, (1), 25 (1971).

    Article  CAS  Google Scholar 

  6. H. Uebel, Z. Alternsforsch.10, 149 (1956).

    CAS  PubMed  Google Scholar 

  7. H. Uebel, Chem. ZentBl129, 1064 (1958).

    Google Scholar 

  8. C. H. W. Horne and J. Ferguson, J. Endocr.54 (1), 47 (1972).

    Article  CAS  PubMed  Google Scholar 

  9. H. P. Von Hahn, J. Miller and G. L. Eichorn, Gerontologia15, 293 (1969).

    Article  Google Scholar 

  10. H. P. Von Hahn, Gerontologia16 (2), 116, (1970).

    Article  Google Scholar 

  11. K. Dakshinamurti and S. Litvak, J. biol. Chem.245, 5600 (1970).

    Article  CAS  PubMed  Google Scholar 

  12. R. L. Boeckx and K. Dakshinamurti, Proc. Can. Fed. Biol. Soc.15, 200 (1972).

    Google Scholar 

  13. R. L. Boeckx and K. Dakshinamurti, Biochem. J.140, 549 (1974).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. K. Dakshinamurti and C. Cheah-Tan, Archs Biochem. Biophys.127, 17 (1970).

    Article  Google Scholar 

  15. K. Dakshinamurti, L. Tarrogo-Litvak and H. C. Hong, Can. J. Biochem.48, 493 (1970).

    Article  CAS  PubMed  Google Scholar 

  16. F. Petrelli, G. Marsili and G. Centioni, Boll. Soc. ital. Biol. sper.49, 1332 (1973).

    CAS  PubMed  Google Scholar 

  17. R. L. Boeckx and K. Dakshinamurti, Biochim. biophys. Acta383, 282 (1975).

    Article  CAS  PubMed  Google Scholar 

  18. F. Petrelli, G. Marsili and P. Moretti, Biochem. exp. Biol.12, (4) 461 (1976).

    CAS  Google Scholar 

  19. K. Dakshinamurti, V. V. Modi and S. P. Mistry, Proc. Soc. exp. Biol. Med.127, 396 (1968).

    Article  CAS  PubMed  Google Scholar 

  20. K. Dakshinamurti and P. R. Desjardins, Can. J. Biochem.46, 1261 (1968).

    Article  CAS  PubMed  Google Scholar 

  21. K. Dakshinamurti, M. A. Sabir and C. bhuvaneswaran, Archs Biochem. Biophys.137, 30 (1970).

    Article  CAS  Google Scholar 

  22. C. Bhuvaneswaran and K. Dakshinamurti, Archs Biochem. Biophys.142 665 (1971).

    Article  CAS  Google Scholar 

  23. C. Bhuvaneswaran and K. Dakshinamurti, Int. J. Biochem.5, 819 (1974).

    Article  CAS  Google Scholar 

  24. D. Jaworek, W. Gruber and H. U. Bergmeyer, Meth. enzym. Analysis4, 2097 (1974).

    Google Scholar 

  25. H. U. Bergmeyer, E. Bernt, F. Schmidt and H. Stork, Meth. enzym. Analysis3, 1196 (1974).

    Google Scholar 

  26. T. E. Weichselbaum, Am. J. clin. Path.16, 40 (1946).

    Article  Google Scholar 

  27. N. Zöllner and K. Kiesch, Z. ges. exp. Med.135, 545 (1962).

    Article  Google Scholar 

  28. A. W. Wahletld, Meth. enzym. Analysis4, 1831 (1974).

    Article  Google Scholar 

  29. C. C. Allain, L. S. Poon, C. S. G. Chan, W. Richond and P. C. Fu, Clin. Chem.20, 470 (1974).

    Article  CAS  PubMed  Google Scholar 

  30. M. A. Andersch and A. J. Scypinski Am. J. clin. Path.17, 571 (1947).

    Article  CAS  PubMed  Google Scholar 

  31. O. A. Bassey, O. H. Lowry and M. T. Brock, J. biol. Chem.164, 321 (1946).

    Article  Google Scholar 

  32. J. Marmur, Meth. Enzym.6, 726 (1963).

    Article  CAS  Google Scholar 

  33. E. R. M. Kay, N. S. Simmons and A. L. Dounce, J. Am. Chem. Soc.74, 1724 (1952).

    Article  CAS  Google Scholar 

  34. M. Swindlehurst, S. J. Berry and W. Firsheim, Biochim. biophys. Acta228, 313 (1971).

    Article  CAS  PubMed  Google Scholar 

  35. W. C. Schneider, Meth. Enzym.3, 680 (1957).

    Article  Google Scholar 

  36. H. Busch, Meth. Enzym.12, 421 (1967).

    Article  Google Scholar 

  37. S. Bram and H. Ris, J. molec. Biol.55, 325 (1971).

    Article  CAS  PubMed  Google Scholar 

  38. M. G. Sevag, D. B. Lackman and J. Smolens, J. biol. Chem.124, 425 (1938).

    Article  CAS  Google Scholar 

  39. I. O. Walker, J. molec. Biol.14, 381 (1965).

    Article  CAS  PubMed  Google Scholar 

  40. W. Denkhaus, D. Heimer and I. Thrum, Gerontologia16, 1 (1970).

    Article  CAS  PubMed  Google Scholar 

  41. G. L. Gianfranceschi, D. Amici and L. Guglielmi, Experientia30, 1049 (1974).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of General Physiology, University of Camerino, Italy

    F. Petrelli, S. Coderoni, P. Moretti, G. Marsili & M. Paparelli

Authors
  1. F. Petrelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Coderoni
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Moretti
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Marsili
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Paparelli
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Petrelli, F., Coderoni, S., Moretti, P. et al. Biotin as a regulator of some haematic parameters and of DNA-content of the liver of old rats. Experientia 34, 193–195 (1978). https://doi.org/10.1007/BF01944672

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01944672

Keywords

Search

Navigation