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Endotoxin-induced acceleration of ovum transport in rabbits

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Summary

Salmonella enteritidis-Boivin endotoxin (1–20 μg/kg) induced accelerated oviductal ovum transport in rabbits in a dose-related manner. Indomethacin prevented this effect. Levels of prostaglandin E and F in uterine vein blood increased following endotoxin injection.

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Authors and Affiliations

  1. Center for Research and Training in Reproductive Biology and Voluntary Regulation of Fertility, Department of Obstetrics and Gynecology, The University of Texas Health Science Center at San Antonio, 78284, San Antonio, Texas, USA

    G. Valenzuela, B. J. Hodgson & M. J. K. Harper

Authors
  1. G. Valenzuela
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  2. B. J. Hodgson
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  3. M. J. K. Harper
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Additional information

Deceased 6 December, 1977.

Thanks are due to Elizabeth Menchaca, Larry Coons and Lenore Weinberg for technical assistance, and to Merck, Sharp, and Dohme for the gift of indomethacin. This work was supported by Rockefeller Foundation, NIH (HD-09339) and WHO (S76119). G. V. is a Rockefeller Foundation Postdoctoral Fellow in Reproductive Biology. Reprint requests to M. J. K. Harper.

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Valenzuela, G., Hodgson, B.J. & Harper, M.J.K. Endotoxin-induced acceleration of ovum transport in rabbits. Experientia 34, 388–389 (1978). https://doi.org/10.1007/BF01923053

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