Summary
The treatment of pigmented guinea-pigs with melatonin aggregates pigmented cells in the retinal pigment epithelium and choroid of the eye. This suggests that melatonin may regulate eye pigmentation in vertebrates.
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We thank Mr M.K. Yip, Mr C.Y. Wat and Miss P. Yip for assistance and Prof. A. Hsieh and Prof. J. Widdicombe for reading the manuscript.
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Pang, S.F., Yew, D.T. Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea-pigs,Cavia porcellus. Experientia 35, 231–233 (1979). https://doi.org/10.1007/BF01920634
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DOI: https://doi.org/10.1007/BF01920634