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Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea-pigs,Cavia porcellus

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The treatment of pigmented guinea-pigs with melatonin aggregates pigmented cells in the retinal pigment epithelium and choroid of the eye. This suggests that melatonin may regulate eye pigmentation in vertebrates.

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References

  1. A. B. Lerner, J. D. Case, Y. Takahashi, T. H. Lee and W. Mori, J. Am. Chem. Soc.80, 2587 (1958).

    Article  CAS  Google Scholar 

  2. A. B. Lerner, J. D. Case and R. V. Heinzelman, J. Am. Chem. Soc.81, 6084 (1959).

    Article  CAS  Google Scholar 

  3. R. J. Wurtman, J. Axelrod and D. E. Kelly, The Pineal. Academic Press, New York 1968.

    Google Scholar 

  4. C. L. Ralph, Am. Zool.16, 35 (1976).

    Article  CAS  Google Scholar 

  5. R. W. Pelham, C. L. Ralph and I. M. Campbell, Biochem. biophys. Res. Commun.46, 1236 (1972).

    Article  CAS  PubMed  Google Scholar 

  6. R. W. Pelham, Endocrinology96, 543 (1975).

    Article  CAS  PubMed  Google Scholar 

  7. S. F. Pang and C. L. Ralph, J. exp. Zool.193, 275 (1975).

    Article  CAS  PubMed  Google Scholar 

  8. J. Arendt, L. Pannier and P. C. Sizonenko, J. clin. Endocr. Metab.40, 347 (1975).

    Article  CAS  PubMed  Google Scholar 

  9. G. M. Vaughan, R. W. Pelham, S. F. Pang, L. L. Laughlin, K. M. Wilson, K. L. Sandock, M. K. Vaughan, S. H. Koslow and R. J. Reiter, J. clin. Endocr. Metab.42, 752 (1976).

    Article  CAS  PubMed  Google Scholar 

  10. F. W. Turek, C. Desjardins and M. Menaker, Science190, 280 (1975); F. W. Turek, C. Desjardins and M. Menaker, Proc. Soc. exp. Biol. Med.151, 502 (1976).

    Article  CAS  PubMed  Google Scholar 

  11. J. E. Martin and D. C. Klein, Science191, 301 (1976).

    Article  CAS  PubMed  Google Scholar 

  12. L. C. Ellis, Am. Zool.16, 67 (1976).

    Article  CAS  Google Scholar 

  13. W. B. Quay, Pineal Chemistry, Thomas, Springfield 1974.

    Google Scholar 

  14. S. F. Pang, C. L. Ralph and D. P. Reilly, Gen. Comp. Endocr.22, 499 (1974).

    Article  CAS  PubMed  Google Scholar 

  15. S. F. Pang, G. M. Brown, L. J. Grota, J. W. Chambers and R. L. Rodman, Neuroendocrinology23, 1 (1977).

    Article  CAS  PubMed  Google Scholar 

  16. G. A. Bubenik, G. M. Brown, I. Uhlir and L. J. Grota, Brain Res.81, 233 (1974).

    Article  CAS  PubMed  Google Scholar 

  17. G. A. Bubenik, G. M. Brown and L. J. Grota, Brain Res.118, 417 (1976a); G. A. Bubenik, G. M. Brown and L. J. Grota, J. Histochem. Cytochem.24, 1173 (1976b); G. A. Bubenik, G. M. Brown and L. J. Grota, Experientia32, 579 (1976c).

    Article  CAS  PubMed  Google Scholar 

  18. A. B. Lerner and J. D. Case, J. invest. Derm.32, 211 (1959).

    Article  CAS  PubMed  Google Scholar 

  19. W. B. Quay and J. T. Bagnara, Archs Inst. Pharmacodyn. Ther.150, 137 (1964).

    CAS  Google Scholar 

  20. C. L. Ralph and H. J. Lynch, Gen. Comp. Endocr.15, 334 (1970).

    Article  CAS  PubMed  Google Scholar 

  21. R. M. Wright and A. B. Lerner, Endocrinology66, 599 (1960).

    Article  CAS  PubMed  Google Scholar 

  22. R. S. Snell, J. invest. Derm.44, 273 (1965).

    Article  CAS  PubMed  Google Scholar 

  23. J. S. McGuire and H. Moller, Nature298, 493 (1965).

    Article  Google Scholar 

  24. D. Mull and C. L. Ralph, Am. Zool.12, 674 (1972).

    Google Scholar 

  25. W. B. Quay, Life Sci.4, 983 (1965).

    Article  CAS  PubMed  Google Scholar 

  26. S. F. Pang, D. T. Yew and H. W. Tsui, Neurosci. Lett., in press (1978).

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We thank Mr M.K. Yip, Mr C.Y. Wat and Miss P. Yip for assistance and Prof. A. Hsieh and Prof. J. Widdicombe for reading the manuscript.

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Pang, S.F., Yew, D.T. Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea-pigs,Cavia porcellus. Experientia 35, 231–233 (1979). https://doi.org/10.1007/BF01920634

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  • DOI: https://doi.org/10.1007/BF01920634

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