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Rapid development of acoustic trauma-induced audiogenic seizure risk in 3 strains of seizure-resistant mice

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Summary

Audiogenic seizure risk can be induced in genetically seizure resistant mice by exposure to an intense noise a few days prior to testing for seizure. This experiment demonstrates that the priming induced seizure risk can develop within 6–16 h after priming. It was argued that this finding suggested an alternative hypothesis of priming involving peripheral auditory mechanisms.

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Authors and Affiliations

  1. Department of Psychology, Monash University, 3168, Clayton, Victoria, Australia

    C. S. Chen

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  1. C. S. Chen
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Additional information

This study was supported by funds from Australian Research Grants Committee. I am grateful for the assistance of Miss Clare Aberdeen.

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Chen, C.S. Rapid development of acoustic trauma-induced audiogenic seizure risk in 3 strains of seizure-resistant mice. Experientia 36, 1194–1196 (1980). https://doi.org/10.1007/BF01976123

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