Summary
The depolarization of cultured astrocytes by GABA and glycine correlates in amplitude and time course with the increase of the extracellular K+-concentration during perfusion with these amino acids. It is suggested that the glial depolarization is caused by an efflux of K+ from neighbouring neurones activated by the amino acid transmitters.
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Hösli, L., Hösli, E., Andrès, P.F. et al. Action of GABA and glycine on the membrane potential of cultured astrocytes and the extracellular K+-concentration. Experientia 36, 1396 (1980). https://doi.org/10.1007/BF01960118
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DOI: https://doi.org/10.1007/BF01960118