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Estimation of pore passage time of red blood cells in normal subjects and patients with renal failure

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Summary

The average transit time of single red blood cells through a nuclepore membrane filter (pore diameter and length, 5 μm and 10 μm, respectively) was measured using an improved method and was shown to be an index of deformability. An increased passage time, indicating reduced deformability, was observed in renal failure.

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Literature

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Authors and Affiliations

  1. Division of Physiology, Research Institute of Applied Electricity, Hokkaido University, Sapporo, Japan

    Y. Kikuchi, M. Horimoto, T. Koyama, Y. Koyama & S. Tozawa

  2. Division of Renal Disease and Hemodialysis, Sapporo Hokushin Hospital, Sapporo, Japan

    Y. Kikuchi, M. Horimoto, T. Koyama, Y. Koyama & S. Tozawa

Authors
  1. Y. Kikuchi
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  2. M. Horimoto
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  3. T. Koyama
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  4. Y. Koyama
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  5. S. Tozawa
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Additional information

Finally we wish to express our thanks to JSPS visiting Prof. Dr I.S. Longmuir, North Carolina State University, USA, for his interest and encouragement, and for correcting the manuscript.

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Kikuchi, Y., Horimoto, M., Koyama, T. et al. Estimation of pore passage time of red blood cells in normal subjects and patients with renal failure. Experientia 36, 325–327 (1980). https://doi.org/10.1007/BF01952304

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  • DOI: https://doi.org/10.1007/BF01952304

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