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Co-polymerization of dopa and cysteinyldopa in melanogenesis in vitro

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Summary

Tyrosinase oxidation of dopa in the presence of varying amounts of 5-S-cysteinyldopa led to the production of pigments whose chemical and physical (colour and solubility) properties are intermediate between those of pure eumelanin-and phaeomelanin-type pigments.

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Authors and Affiliations

  1. Institute for Comprehensive Medical Science, School of Medicine, Fujita-Gakuen University, 470-11, Toyoake, Aichi, Japan

    S. Ito, E. Novellino, F. Chioccara, G. Misuraca & G. Prota

  2. Istituto di Biorganica, Facoltà di Farmacia, Napoli

    S. Ito, E. Novellino, F. Chioccara, G. Misuraca & G. Prota

  3. Istituto di Chimica Organica e Biologica dell'Università, Via Mezzocannone 16, I-80134, Napoli, Italy

    S. Ito, E. Novellino, F. Chioccara, G. Misuraca & G. Prota

Authors
  1. S. Ito
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  2. E. Novellino
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  3. F. Chioccara
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  4. G. Misuraca
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  5. G. Prota
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Additional information

Acknowledgment. This work was supported in part by a grant from CNR, Rome, within the frame of the project ‘Controllo della crescita neoplastica’.

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Ito, S., Novellino, E., Chioccara, F. et al. Co-polymerization of dopa and cysteinyldopa in melanogenesis in vitro. Experientia 36, 822–823 (1980). https://doi.org/10.1007/BF01978591

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  • DOI: https://doi.org/10.1007/BF01978591

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