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Depressant effects of major tranquillizers on contact hypersensitivity to picryl chloride in the mouse

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Summary

Chlorpromazine, levomepromazine, thioproperazine, promethazine and haloperidol were found to significantly depress contact hypersensitivity to picryl chloride in the mouse, a model of cell-mediated immune response.

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Authors and Affiliations

  1. Laboratoire de Pharmacologie, Faculté de Médecine Alexis Carrel, rue Guillaume Paradin, F-69008, Lyon, France

    J. Descotes & J. Cl. Evreux

Authors
  1. J. Descotes
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  2. J. Cl. Evreux
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The skilled technical assistance of R. Tedone is warmly acknowledged.

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Descotes, J., Evreux, J.C. Depressant effects of major tranquillizers on contact hypersensitivity to picryl chloride in the mouse. Experientia 37, 1004–1005 (1981). https://doi.org/10.1007/BF01971805

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