Skip to main content
Log in

Effect of streptozotocin diabetes on adenosine-5′-triphosphate, oxygen consumption and steroidogenesis in testis mitochondria from rats

  • Specialia
  • Chemica, Biochimica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

The activity of the enzyme cleaving the side-chain of cholesterol (rate limiting step in steroidogenesis) was considerably reduced in experimentally induced diabetes. This result was accompained by both an increase in oxygen consumption and an increase in ATP synthesis. Insulin treatment prevented them.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. V. G. Foglia, J. M. Rosner, M. Ramos and B. E. Lema, Horm. Metab. Res.1, 72 (1969).

    Article  CAS  PubMed  Google Scholar 

  2. A. Oksanen, Horm. Res.6, 138 (1975).

    Article  CAS  PubMed  Google Scholar 

  3. B. E. Howland and E. J. Zebrowski, Horm. Metab. Res.8, 465 (1976).

    Article  CAS  PubMed  Google Scholar 

  4. G. Paz and Z. T. Homonnai, Int. J. Androl.2, 353 (1979).

    Article  CAS  Google Scholar 

  5. M. J. Dimino, T. R. Chavis and J. R. Downing, Endocrinology106, 1528 (1980).

    Article  CAS  PubMed  Google Scholar 

  6. E. C. Slater, Meth. Enzymol.10, 18 (1967).

    Google Scholar 

  7. J. Robinson and P. M. Stevenson, Eur. J. Biochem.24, 18 (1971).

    Article  CAS  PubMed  Google Scholar 

  8. C. Libertun, J. A. Moguilevsky, O. Schiaffini and V. Foglia, Experientia25, 196 (1969).

    Article  CAS  PubMed  Google Scholar 

  9. O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall, J. biol. Chem.193, 265 (1951).

    Article  CAS  PubMed  Google Scholar 

  10. G. Paz and Z. T. Homonnai, Experientia35, 1412 (1979).

    Article  CAS  PubMed  Google Scholar 

  11. C. Desjardins, Biol. Reprod.24, 1 (1981).

    Article  CAS  PubMed  Google Scholar 

  12. V. I. Uzgiris, E. N. McIntosh, C. Alonso and H. A. Salhanick, Biochemistry10, 2916 (1970).

    Article  Google Scholar 

  13. M. J. Dimino, D. M. Lloyd, E. A. Elfont, D. W. Peters and R. J. Schubatis, Endocrinology99, 1377 (1976).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Benitez, A., Díaz, J.P. Effect of streptozotocin diabetes on adenosine-5′-triphosphate, oxygen consumption and steroidogenesis in testis mitochondria from rats. Experientia 38, 907–908 (1982). https://doi.org/10.1007/BF01953646

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01953646

Keywords

Navigation