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Differential effects of cadmium and mercury on amino acid and sugar transport in the bullfrog small intestine

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Summary

Amino acid transport in the bullfrog small intestine was specifically inhibited by application of Cd2+ to the mucosal fluid. This inhibition was dose-dependent, reversible and competitive in nature. In contrast, Hg2+ inhibited both amino acid transport and sugar transport: the inhibition by Hg2+ was non-graded, irreversible and non-competitive in nature.

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Author notes

  1. W. Tsuchiya

    Present address: Department of Dermatology, Faculty of Medicine, Kyoto University, 606, Kyoto, Japan

Authors and Affiliations

  1. Department of Physiology, Faculty of Medicine, Kyoto University, 606, Kyoto, Japan

    W. Tsuchiya & Y. Okada

Authors
  1. W. Tsuchiya
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  2. Y. Okada
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Additional information

Acknowledgements. The authors are indebted to Professor A. Inouye for his advice to this study and to Professor M. Kuno for his reading the manuscript.

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Tsuchiya, W., Okada, Y. Differential effects of cadmium and mercury on amino acid and sugar transport in the bullfrog small intestine. Experientia 38, 1073–1075 (1982). https://doi.org/10.1007/BF01955374

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  • DOI: https://doi.org/10.1007/BF01955374

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