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High resolution of heterochromatin ofDrosophila melanogaster by distamycin A

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  • Genetics, Developmental Biology, Aging
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Summary

A DNA-binding AT-specific antibiotic, distamycin A, was used as inhibitor of the condensation process of the heterochromatic regions inDrosophila melanogaster embryonic cells. By this treatment the structural organization of heterochromatin at interphase is preserved until metaphase. The different patterns observed are interpreted as chronological steps in the condensation process.

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References

  1. Brutlag, D., Carlson, M., Fry, K., and Hsieh, T. S., Cold Spring Harb. Symp. quant. Biol.42 (1977) 1137.

    Article  Google Scholar 

  2. Zimmer, C., Prog. Nucleic Acid Res. molec. Biol.15 (1975) 285.

    Article  CAS  Google Scholar 

  3. Comings, D. E., Chromosoma52 (1975) 229.

    Article  CAS  PubMed  Google Scholar 

  4. Lin, M. S., Comings, D. E., and Alfi, S., Chromosoma60 (1977) 15.

    Article  CAS  PubMed  Google Scholar 

  5. Echalier, G., and Ohanessian, A., In Vitro6 (1970) 162.

    Article  CAS  PubMed  Google Scholar 

  6. Peacock, W. J., Lohe, A. R., Gerlach, W. L., Dunsmuir, P., Dennis, E. S., and Appels, R., Cold Spring Harb. Symp. quant. Biol.42 (1977) 1121.

    Article  Google Scholar 

  7. Slizynski, B. M., Proc. R. Soc. EdinburghB 62 (1945) 114.

    Google Scholar 

  8. Barr, H. J., and Ellison, J. R., Chromosoma39 (1972) 53.

    Article  CAS  PubMed  Google Scholar 

  9. Pimpinelli, S., Gatti, M., and De Marco, A., Nature, Lond.256 (1975) 335.

    Article  CAS  PubMed  Google Scholar 

  10. Lakhotia, S. C., and Roy, J. K., Exp. Cell Res.132 (1981) 423.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Biology, University of Milan, Via Celoria 26, I-20133, Milan, Italy

    S. Faccio Dolfini & A. Bonifazio Razzini

Authors
  1. S. Faccio Dolfini
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  2. A. Bonifazio Razzini
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Additional information

We wish to thank Prof. C. Barigozzi for many helpful discussions and for critical reading of the manuscript. The comments of Prof. D. Schweizer, Institute of Botany, University of Vienna, are also gratefully acknowledged.

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Faccio Dolfini, S., Bonifazio Razzini, A. High resolution of heterochromatin ofDrosophila melanogaster by distamycin A. Experientia 39, 1402–1404 (1983). https://doi.org/10.1007/BF01990127

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  • DOI: https://doi.org/10.1007/BF01990127

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