Skip to main content
SpringerLink
Log in

Aspects of interastrocytic gap junctions in blood-brain barrier in the experimental penumbra area, revealed by transmission electron microscopy and freeze-fracture

  • Published:
Experientia Aims and scope Submit manuscript

Summary

Interastrocytic gap junctions in the blood-brain barrier of the experimental penumbra area were studied in the cat caudate nucleus 1 h after ischemia. Transmission electron microscopy and freeze-fracture studies revealed only slight changes in gap junctions between astrocytes, indicating that these junctions are very resistant to hypoxia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Symon, L., Crockard, H.A., Dorsch, N.W.C., Branston, N.M., and Juhasz, J., Stroke6 (1975) 482.

    Article  CAS  PubMed  Google Scholar 

  2. Gutierrez-Diaz, J.A., Cuevas, P., Dujovny, M., Diaz, F.G., and Ausman, J.I., Neurosci. Lett., Suppl.10 (1982) 225.

    Google Scholar 

  3. Shaller, Ch.A., Jacques, S., and Shelden, Ch., Surg. Neurol.14 (1980) 433.

    CAS  PubMed  Google Scholar 

  4. Forsmann, W.G., Ito, W., Weihe, E., Aoki, A., Dyn, M., and Fawcett, D.W., Anat. Rec.188 (1977) 307.

    Article  Google Scholar 

  5. Brierley, J.B., Melbrum, B.S., and Brown, A.W., Archs Neurol.29 (1973) 367.

    Article  CAS  Google Scholar 

  6. Branton, D., Bullivant, S., Gilula, N.B., Karnovsky, M.J., Moor, H., Muhlethaler, K., Northcote, D.H., Packer, L., Satir, B., Satir, P., Speth, V., Staehelin, L.A., Steeve, R.L., and Weinstein, R.S., Science190 (1979) 54.

    Article  Google Scholar 

  7. Peracchia, C., Int. Rev. Cytol.66 (1980) 81.

    Article  CAS  PubMed  Google Scholar 

  8. Landis, D.M.D., and Reese, T.S., J. Cell Biol.60 (1974) 316.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Massa, P.T., and Mugnaini, E., Neuroscience7 (1982) 523.

    Article  CAS  PubMed  Google Scholar 

  10. Cuevas, P., Gutierrez-Diaz, J.A., Dujovny, M., Diaz, F.G., and Ausman, J.I., Selective cerebral ischemia in cats. Transmission electron microscopy (TEM) and freeze-fracture (FF) studies, in: Microsurgery for Stroke. Ed. H. Handa. Tokyo 1980.

    Google Scholar 

  11. Landis, D.M.D., and Reese, T.S., J. Cell Biol.88, 1981, 660.

    Article  CAS  PubMed  Google Scholar 

  12. Marchesi, V.T., Sears, M.V., and Barnnett, R.J., Invest. Ophthalm. Molec.3 (1964) 1.

    CAS  Google Scholar 

  13. Varon, S.S., and Somjen, G.G. Neurosci. Res. Prog. Bull.17 (1979) 147.

    Google Scholar 

  14. McGreer, E.G., and McGreer, P.L., J. Neurochem.32 (1979) 1071.

    Article  Google Scholar 

  15. Loewenstein, W.R., Kanneo, Y., and Socolar, S.J., Fedn Proc.37 (1978) 2645.

    CAS  Google Scholar 

  16. Hossman, K., and Sato, K., Stroke8 (1977) 77.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Investigation. Histology, and Department of Neurosurgery, Centro Especial Ramon y Cajal, Ctra. Colmenar, Km 9.100, 34, Marid, Spain

    P. Cuevas, J. A. Gutierrez Diaz, D. Reimers, M. Dujovny, F. G. Diaz & J. I. Ausman

  2. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA

    P. Cuevas, J. A. Gutierrez Diaz, D. Reimers, M. Dujovny, F. G. Diaz & J. I. Ausman

Authors
  1. P. Cuevas
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. A. Gutierrez Diaz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. Reimers
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. Dujovny
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. G. Diaz
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. I. Ausman
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Authors are grateful to M. Guerricabeitia and Ch. Bourdier for their technical and secretarial assistance.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cuevas, P., Gutierrez Diaz, J.A., Reimers, D. et al. Aspects of interastrocytic gap junctions in blood-brain barrier in the experimental penumbra area, revealed by transmission electron microscopy and freeze-fracture. Experientia 40, 471–473 (1984). https://doi.org/10.1007/BF01952391

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01952391

Keywords

Search

Navigation