Summary
The effect of mycotoxin (T-2 toxin) on catecholamines and Na+, K+-ATPase activities in rat epididymis has been evaluated. Dopamine and norepinephrine levels were significantly elevated in the caput and corpus regions whereas their levels remained unchanged in the caudal part of the epididymis. Na+, K+-ATPase activity was significantly increased in all the three regions of rat epididymis as a result of the toxin treatment. These changes may suggest an adverse effect on epididymal functions in rats.
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Jones, R., and Glover, T. D., in: The biology of gamate, p. 367. Eds J. C. Duckett and P. A. Racey. Academic Press, London 1975.
Brooks, D. E., in: The spermatozoon, p. 23. Eds D. W. Fawcett and J. M. Bedford. Urban and Schwarzenberg, Baltimore 1979.
Brooks, D. E., Biochem. J.174 (1978) 741.
Ueno, Y., in: Advances in nutritional research, p. 301. Ed. H. H. Draper. Plenum Publishing Corporation, New York 1980.
Stojanoic, T., Djuric, B. M., and Marsulja, B. B., Experientia36 (1980) 48.
Fiske, C. H., Subbarow, Y., J. biol. Chem.66 (1965) 375.
Lowry, O. H., Rosebrough, N. J., Farr A. L., and Randall, R. J., J. biol. Chem.193 (1951) 265.
Sadavongvivad, C., Br. J. Pharmac.38 (1970) 353.
Urry, R. L., and Ellis, L. C., in: The testis, vol. 4, p. 315. Eds A. D. Johnson and W. R. Gomes. Academic Press, New York 1977.
Davis, J. R., Langford, G. A., and Kirby, P. J., in: The testis, vol. 1, p. 282. Eds A. D. Johnson, W. R. Gomes and N. L. Van Demark. Academic Press, New York 1970.
Eliasson, R., and Risley, P. L., Acta physiol. scand.73 (1968) 311.
Farias, R. N., Bloj, B., Morero, R. D., Sineriz, F., and Trucco, R. E., Biochim. biophys. Acta415 (1975) 231.
Barbara, A. H., and Eaton, M., Eur. J. Pharmac.34 (1975) 241.
Herd, P. A., Howitz, B. A., and Srithy, R. E., Experientia26 (1970) 825.
Svoboda, P., and Mosinger, B., Biochem. Pharmac.30 (1981) 433.
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Singh, U.S., Ram, G.C. & Srivastava, A.K. Effect of mycotoxin (T-2 toxin) on catecholamine and Na+, K+-ATPase levels in rat epididymis. Experientia 41, 363–364 (1985). https://doi.org/10.1007/BF02004506
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DOI: https://doi.org/10.1007/BF02004506