Summary
Using a pulse-labeling technique,14C-adenosine uptake into pyrimidine 5′-nucleotidase (P5N) deficient erythrocytes (RBC) was found to be impaired. The Lineweaver-Burk plot showed Km values of 2.0×10−3 mM and 0.2 ×10−3 mM for normal RBC and P5N deficient RBC, respectively. These results indicate that P5N is one of regulators of the adenosine transport system and/or is associated with adenosine carrier protein.
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Kagimoto, T., Tomino, S. & Takatsuki, K. Adenosine uptake in pyrimidine 5′-nucleotidase deficient human erythrocytes via a high affinity transport system. Experientia 41, 366–368 (1985). https://doi.org/10.1007/BF02004508
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DOI: https://doi.org/10.1007/BF02004508