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Normetanephrine and metanephrine oxidized by both types of monoamine oxidase

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  • Biochemistry and Biophysics, Metabolism, Neurobiology, Pharmacology
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Summary

Both normetanephrine and metanephrine were found to be oxidized by both types of monoamine oxidase in mouse liver mitochondria. Both Km and Vmax values of type B MAO for both substrates were higher than those of type A MAO, which caused the shift of inhibition curves with clorgyline and deprenyl according to the increase in substrate concentration.

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Authors and Affiliations

  1. Department of Legal Medicine, Hamamatsu University School of Medicine, 431-31, Hamamatsu, Japan

    O. Suzuki & T. Matsumoto

  2. Division of Oncology, First Department of Surgery, Nagoya University School of Medicine, 466, Nagoya, Japan

    O. Suzuki & T. Matsumoto

Authors
  1. O. Suzuki
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  2. T. Matsumoto
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Suzuki, O., Matsumoto, T. Normetanephrine and metanephrine oxidized by both types of monoamine oxidase. Experientia 41, 634–636 (1985). https://doi.org/10.1007/BF02007695

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  • DOI: https://doi.org/10.1007/BF02007695

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