Summary
A radiologically normal human nucleus pulposus was extracted with 4 M guanidinium chloride and the non-collagenous proteins separated from the proteoglycans by dissociative density gradient centrifugation. Lysozyme was identified as a matrix constituent of the normal, mature human nucleus pulposus.
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Supported by Public Health Service Training Grant ES-07088.
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Sorce, D.J., McDevitt, C.A., Greenwald, R.A. et al. Protein and lysozyme content of adult human nucleus pulposus. Experientia 42, 1157–1158 (1986). https://doi.org/10.1007/BF01941291
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DOI: https://doi.org/10.1007/BF01941291