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Isolation of a hexaprenylhydroquinone sulfate from the marine spongeDysidea sp. as an H, K-ATPase inhibitor

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Summary

A hexaprenylhydroquinone sulfate has been isolated as an H, K-ATPase inhibitor from a marine spongeDysidea sp. It also inhibited phospholipase A2 as well as secretion of gastric acid in rats.

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Authors and Affiliations

  1. Laboratory of Marine Biochemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

    N. Fusetani, M. Sugano, S. Matsunaga & K. Hashimoto

  2. Central Research Laboratories, Yamanouchi Pharmaceutical Co. Ltd, Itabashi-ku, Tokyo, Japan

    H. Shikama, A. Ohta & H. Nagano

Authors
  1. N. Fusetani
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  2. M. Sugano
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  3. S. Matsunaga
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  4. K. Hashimoto
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  5. H. Shikama
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  6. A. Ohta
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  7. H. Nagano
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Additional information

Bioactive Marine Metabolites XVIII; Part XVII: Fusetani, N., Yasukawa, K., Matsunaga, S., and Hashimoto, K., Tetrahedron Lett.28 (1987) 1187.

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Fusetani, N., Sugano, M., Matsunaga, S. et al. Isolation of a hexaprenylhydroquinone sulfate from the marine spongeDysidea sp. as an H, K-ATPase inhibitor. Experientia 43, 1233–1234 (1987). https://doi.org/10.1007/BF01945539

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  • DOI: https://doi.org/10.1007/BF01945539

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