Summary
Rat brain homogenate was preloaded with [3H]noradrenaline or [3H]GABA and stimulated with high K+. Tetanus toxin and botulinum A neurotoxin partially prevent the evoked [3H]noradrenaline release in the same range of toxin concentrations starting below 10−10M. In contrast, release of γ-amino butyric acid (GABA) is much more sensitive to tetanus than to botulinum A toxin.
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References
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Habermann, E. Inhibition by tetanus and botulinum A toxin of the release of [3H]noradrenaline and [3H]GABA from rat brain homogenate. Experientia 44, 224–226 (1988). https://doi.org/10.1007/BF01941714
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DOI: https://doi.org/10.1007/BF01941714