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Some extracellular matrix elements as markers of ‘capillary tunnels’ in hypertrophied rat heart

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Abstract

We studied the distribution of the extracellular matrix proteins fibronectin (FN) and laminin (LM) in the hypertrophied hearts of spontaneously hypertensive rats (SHR), using an immunofluorescence method with specific antibodies. The immunohistochemical reaction was positive in the cytoplasm of some hypertrophied cardiomyocytes. The results showed that FN and LM can be used as markers for tunnels, i.e. intracardiocytic invaginations of the sarcolemma. The tunnels observed contained capillaries.

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Authors and Affiliations

  1. Department of Pathological Anatomy, Institute of Biostructure, Medical Academy of Warsaw, Chalubińskiego 5, PL-02-004, Warsaw, Poland

    A. Ratajska, Z. Gawlik & E. Fiejka

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  1. A. Ratajska
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  2. Z. Gawlik
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  3. E. Fiejka
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Ratajska, A., Gawlik, Z. & Fiejka, E. Some extracellular matrix elements as markers of ‘capillary tunnels’ in hypertrophied rat heart. Experientia 47, 964–968 (1991). https://doi.org/10.1007/BF01929893

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  • DOI: https://doi.org/10.1007/BF01929893

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