Abstract
On the basis of a study of electrophilic substitution reactions (the Mannich reaction and bromination) it was shown that 4,7-diazaindoles react with greater difficulty with “soft” electrophilic agents than indoles or 4- and 7-monoazaindoles. 3-Substituted and 1,3-disubstituted 4,7-diazaindoles containing amino(dialkylamino)alkyl substituents in the 1 or 3 positions were synthesized.
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S. Klutchko, H. V. Hansen, and R. I. Meltzer, J. Org. Chem., 30, 3454 (1965).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 848–852, June, 1976.
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Azimov, V.A., Yakhontov, L.N. Synthesis of 3-substituted and 1,3-disubstituted 4,7-diazaindoles. Chem Heterocycl Compd 12, 707–710 (1976). https://doi.org/10.1007/BF00742464
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DOI: https://doi.org/10.1007/BF00742464