Summary
While the mycelium of streptomycin (SM) producer takes up extracellular SM, it eliminates the accumulated SM after phosphorylation with SM 6-kinase. The rate of uptake of SM, rather than the content of SM 6-kinase in mycelium, limits the capacity of mycelium to phosphorylate the extracellular SM.
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Nimi, O., Sugiyama, M., Kameoka, H. et al. Fate of streptomycin in mycelium of the producer organism. Biotechnol Lett 3, 239–244 (1981). https://doi.org/10.1007/BF00154651
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DOI: https://doi.org/10.1007/BF00154651