Abstract
Two cohorts of men aged 49–59 at entry, representing cluster samples of two rural areas in Northern and Central Italy, for a total of 1712 subjects have been followed-up for 20 years within an epidemiological study originally designed for cardiovascular disease. After 20 years, only 41 men have been judged to have remained substancially healthy throughout the observation period, i.e. free from a number of major diseases. Univariate and multivariate analyses trying to predict the maintenance of health status showed that among 21 selected characteristics only the following one had a significant power: age, cigarette smoking (adverse effect) and vital capacity( favourable effect). A minor role was also played by the body mass index (adverse effect) and forced expiratory volume (favourable effect).
Those who did not remain healthy exibited a greater increase in blood pressure and body mass index.
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References
Conti S., Farchi G. and Menotti A. (1983): Coronary risk factors and excess mortality from all causes and specific causes. - Int. J. Epidem. 12: 301–307.
Dawber T.R. (1980): The Framingham Study. The Epidemiology of atherosclerotic disease. Harward Univ. Press, Cambridge Mass. and London, England.
Ducimetiere P., Richard J.L., Cambien F., RakotovaoR. and Claude J.R. (1980): Coronary heart disease in middle-aged Frenchmen. Comparison between Paris prospective study, Seven Countries Study and Pooling Project. - Lancet, 1: 1346–1350.
Dyer A.R., Stamler J., Berkson D.M. and LindbergH.A. (1975): Relationship of relative weight and body mass index to 14 year mortality in the Chicago Peoples Gas Company Study. - J. Chronic Dis., 28: 109–123.
Goldbourt U., Medalie J.H. and Neufeld H.N. (1975): Clinical myocardial infarction on a five-years period. III. A multivariate analysis of incidence. The Israel ischaemic heart disease study. -J. Chronic Dis., 28: 217–237.
Keys A., Aravanis C., Blackburn H., Buzina R., Djordjevic B.S., Dontas A.S., Fidanza F., KarvonenM.J., Kimura N., Menotti A., Mohacek F., NedeljkovicS., Puddu V., Punsar R., Taylor H.L. and VonBuchen F.S.P. (1980): Seven Countries. A multivariate analysis of Coronary Heart Disease and Death. - Harward University Press, Cambridge Mass, London.
Keys A., Aravanis C., VanBuchem F.S.P., BlackburnH., Buzina R., Djordjevic B.S., Dontas A.S., Fidanza F., Karvonen M.J., Kimura N., Menotti A., Nedeljkovic S., Puddu V., Punsar S. and TaylorH.L. (1981): The diet and all causes of death rate in the Seven Countries Study. - Lancet, 2: 58–61.
Keys A., Menotti A., Aravanis C., BlackburnH., Djordjevic B.S., Buzina R., Dontas A.S., FidanzaF., Karvonen M.J., Kimura N., Mohacek I., NedeljkovicS., Puddu V., Punsar S., Taylor H., Conti S., Kronhont D. and Tushinza H. (1984): The Seven Countries: 2289 deaths in 15 years. - Prev. Med., 13: 141–154.
Keys A., Taylor H.L., Blackburn H., Brozek J., Anderson J.T. and Simonson E. (1971): Mortality and coronary heart disease among men studied for 23 years. - Arch. Intern. Med., 128: 201–214.
Keys A. (Ed.) (1970): Coronary heart disease in seven countries. - Circulation, 41: Suppl. I: 1–211.
Menotti A., Conti S., Giampaoli S., Mariotti S. and Signoretti P. (1980): Coronary risk factors predicting coronary and other causes of death in fifteen years. - Acta Cardiol., 35: 107–120.
Menotti A., Conti S., Dima F., Giampaoli S., GiuliB., Rumi A., Seccareccia F. and Signoretti P. (1983): Prediction of all causes of death as a function of some factors commonly measured in cariovascular population surveys. - Prev. Med., 12: 318–325.
Menotti A. (1982): Coronary risk factors and mortality for coronary and non-coronary events. In: Lenzi S., Descovich G.C. (Eds). Atherosclerosis, Clinical Evaluation and Therapy. MTP Press, Lancaster, Boston, The Hague.
Pooling Project Research Group (1978): Relationship of blood pressure, serum cholesterol, smoking habits, relative weight and ECG abnormalities to incidence of major coronary events: final report of the Pooling Project. - J. Chron. Dis., 31: 201–306.
Raynor W.J., Shekelle R.B., Rossof A.H., Maliza C. and Paul O., (1981): High blood pressure and 17 year mortality in the Western Electric Health Study. - Amer. J. Epidemiol., 113: 371–377.
Shurtleff D. (1974): Some characteristics related to the incidence of cardiovascular disease and death: Framingham study, 18 year follow-up, in ≪ The Framingham Study. An Epidemiological Investigation of Cardiovascular Disease ≫ (W.B. Kannel and T. Gordon, Eds.), Section 30. DREW Publication (NIH) 74–599.
Walker S.H. and Duncan W. (1967): Estimation of the probability of an event as a function of several independent variables. - Biometrika 54: 167–179.
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Menotti, A., Conti, S., Farchi, G. et al. The prediction of future health in healthy middle-aged men. Eur J Epidemiol 2, 233–239 (1986). https://doi.org/10.1007/BF00211537
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DOI: https://doi.org/10.1007/BF00211537