Abstract
Using Gibbs Energies of compounds, as well as Gibbs Energy changes and equilibrium constants of biochemical reactions, the contributions of functional groups to the Gibbs Energy (in aqueous solution, temperature 25°C, and pH=7) have been estimated. These contributions allow the estimation of the Gibbs Free Energy and the equilibrium constant of a biochemical reaction, given the structure of the reactants and products.
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Mavrovouniotis, M.L., Bayol, P., Lam, TK.M. et al. A group contribution method for the estimation of equilibrium constants for biochemical reactions. Biotechnol Tech 2, 23–28 (1988). https://doi.org/10.1007/BF01874203
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DOI: https://doi.org/10.1007/BF01874203