Abstract
β- and γ-Cyclodextrin (CD) and heptakis-2,6-di-O-methyl-β-cyclodextrin (DIMEB) form soluble inclusion compounds with mefenorex (MEF); with α-CD a partial inclusion occurs. No solid inclusion compound could be obtained with the four CDs. β-, γ-CD and DIMEB, but not α-CD, enhance the nitrosation rate of MEF if the nitrosation assay procedure (NAP test) is applied. During this reaction with β- and γ-CD, solid inclusion compounds of the CDs and nitrosomefenorex (NMEF) precipitate.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
K.-H. Frömming, V. Wedelich, and W. Mehnert,J. Incl. Phenom. 2, 605 (1984).
V. Wedelich, W. Mehnert, and K.-H. Frömming,J. Incl. Phenom. 5, 621 (1987) (this issue).
J. Szejtli, A. Liptak, P. Fügedi, P. Nanasi, and A. Neszmelyi,Stärke 32, 165 (1980).
B. Casu, M. Reggiani, G. G. Gallo, and A. Vigevani,Tetrahedron 24, 803 (1968).
Author information
Authors and Affiliations
Additional information
Part of the Ph.D. thesis of V. Wedelich, Freie Universität Berlin, 1985.
Rights and permissions
About this article
Cite this article
Frömming, K.H., Wedelich, V. & Mehnert, W. Nitrosation of mefenorex in the presence of cyclodextrins. Journal of Inclusion Phenomena 5, 625–629 (1987). https://doi.org/10.1007/BF00663003
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00663003