Skip to main content
SpringerLink
Log in

Transient DSC, a Novel and Rapid Method for Assessing Pharmaceutical Powder Compacts

  • Published:
Journal of Thermal Analysis and Calorimetry Aims and scope Submit manuscript

Abstract

The previously described method involving the use of transient DSC was applied to pharmaceutical powder compacts and to ceramic powder compacts. The samples were prepared by compressing powders of pentaerythritol tetraacetate and two kinds of alumina powder (differing in particle size distribution) up to a pressure of 20 MPa by using a jig. For pentaerythritol tetraacetate, a linear relationship was obtained between the parameter obtained by DSC and the compaction pressure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. E. Klar and W. M. Shafer, Int. J. Pow. Met., 5(2) (1969) 5.

    Google Scholar 

  2. E. Klar and W. M. Shafer, Int. J. Pow. Met., 5(4) (1969) 5.

    Google Scholar 

  3. J. S. Hardman and B. A. Lilley, Contemp. Phys., 15 (1974) 517.

    CAS  Google Scholar 

  4. Product brochure, Perkin Elmer Japan.

  5. R. Ozao and M. Ochiai, American Ceramic Society Annual Meeting SIV-005–98 (1998).

  6. R. Ozao, H. Ogura, M. Ochiai and S. Tsutsumi, J. Thermal Anal., 49 (1997) 961.

    Article  CAS  Google Scholar 

  7. R. Ozao, M. Ochiai, Y. Ichimura, H. Takahashi and T. Takano, American Ceramic Society Annual Meeting BS11–019–98 (1998).

  8. N. D. Osborne, Part. Part. Syst. Charact., 9 (1992) 202.

    Article  CAS  Google Scholar 

  9. R. Ozao, H. Ogura, M. Ochiai and S. Tsutsumi, J. Thermal Anal., 49 (1997) 1305.

    Article  CAS  Google Scholar 

  10. R. Ozao, M. Ochiai, Y. Ichimura, H. Takahashi and T. Takano, in preparation.

  11. W. Woodside and J. H. Mesmer, J. Appl. Phys., 32 (1961) 1688.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. North Shore College of SONY Institute, Atsugi, 243-8501

    R. Ozao & M. Ochiai

  2. Seiko Instruments Inc., Chiba, 261-8507

    Y. Ichimura & H. Takahashi

  3. Waseda University, Tokyo, 169-8555, Japan

    T. Takano

Authors
  1. R. Ozao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Ochiai
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Y. Ichimura
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. Takahashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. T. Takano
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ozao, R., Ochiai, M., Ichimura, Y. et al. Transient DSC, a Novel and Rapid Method for Assessing Pharmaceutical Powder Compacts. Journal of Thermal Analysis and Calorimetry 56, 1311–1316 (1999). https://doi.org/10.1023/A:1010198221472

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1010198221472

Search

Navigation