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Synthesis of peptide nucleic acid-peptide chimeras carrying the c-myc tag-sequence

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Abstract

The preparation of peptide nucleic acids (PNA)carrying a c-myc tag-peptide sequence isdescribed. These PNA-peptide chimeras have higheraffinity to complementary DNA than unmodifiedoligonucleotides. Moreover, they can be used asnonradioactive probes with sensitivity similar toother nonradioactive methods.

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Correspondence to Ramon Eritja.

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Gottschling, D., Seliger, H., Tarrasón, G. et al. Synthesis of peptide nucleic acid-peptide chimeras carrying the c-myc tag-sequence. Letters in Peptide Science 7, 35–39 (2000). https://doi.org/10.1023/A:1008933416669

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  • DOI: https://doi.org/10.1023/A:1008933416669

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