Skip to main content
SpringerLink
Log in

Kinetic and mechanistic studies on the oxidation of arginine and histidine by chloramine-T in hydrochloric acid medium

  • Published:
Reaction Kinetics and Catalysis Letters Aims and scope Submit manuscript

Abstract

The oxidation of amino acids by chloramine-T (CAT) in HCl medium at 30°C indicates simultaneous catalysis by H+ and Cl− ions in the HCl concentration range of 0.04–0.12 M. The reaction is first order with respect to concentrations [CAT], [H+] and [arginine], but zero order with respect to [histidine]. The rate depends also on Cl− concentration following 0.7th order. At HCl concentrations >0.12 M, the rate equation is:w=k[CAT] [amino acid]0.6 and is independent of the [Cl−]. A suitable mechanism has been suggested.

Abstract

При окислении аминокислот хлорамином-T (CAT) в среде HCl (30°C) установлен одновременный катализ как ионами H+, так и ионами Cl− при [HCl]=0,04–0,12M. Для скорости реакции наблюдается первый порядок по [CAT], [H+] и [аргинин] и нулевой порядок по [гистидин]. Скорость реакции также зависит от [Cl−]0,7. При [HCl]>0,12M скорость=k · [CAT][аминокислота]0,6 и не зависит от [Cl−]. Предложен возможный механизм процесса.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. Kumar, A. K. Bose, S. P. Mushran: Monatsh. Chem.,106, 13 (1975).

    Google Scholar 

  2. A. I. Vogel: Quantitative Organic Analysis, p. 708, Longman Greens, London, 1958.

    Google Scholar 

  3. D. S. Mahadevappa, N. M. M. Gowda: Talanta,22, 771 (1975).

    Google Scholar 

  4. S. Soloway, A. Lipschietz: Anal. Chem.,22, 898 (1952).

    Google Scholar 

  5. E. S. Amis: J. Chem. Ed.,30, 351 (1953); Anal. Chem.,27, 1672 (1955).

    Google Scholar 

  6. E. Bishop, V. J. Jennings: Talanta,1, 197 (1958).

    Google Scholar 

  7. J. C. Morris, J. A. Salazar, M. A. Wineman: J. Amer. Chem. Soc.,70, 2036 (1948).

    Google Scholar 

  8. E. S. Gould: Mechanism and Structure in Organic Chemistry, p. 650, Holt, Rinehart and Winston, N. Y., 1964.

    Google Scholar 

  9. D. S. Mahadevappa, M. S. Ahmed, N. M. M. Gowda: Indian J. Chem. (in press).

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Mysore, Manasa Gangotri, 570006, Mysore, India

    D. S. Mahadevappa, K. S. Rangappa & N. M. M. Gowda

Authors
  1. D. S. Mahadevappa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. S. Rangappa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. M. M. Gowda
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mahadevappa, D.S., Rangappa, K.S. & Gowda, N.M.M. Kinetic and mechanistic studies on the oxidation of arginine and histidine by chloramine-T in hydrochloric acid medium. React Kinet Catal Lett 15, 13–19 (1980). https://doi.org/10.1007/BF02062378

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02062378

Keywords

Search

Navigation