Summary
Mixed-ligand complex formation of copper(I) with 2,2′,2″-terpyridine (terpy) and various biologically significant sulfurcontaining amino acids, L′ [L′ = cysteine, penicillamine,N-acetylcysteine andN-acetylpenicillamine] was investigated. WithN-acetylcysteine andN-acetylpenicillamine, copper(I) complexes [Cu(terpy)L′]HCl have been isolated and characterised. The amino acid in each case bonds to the copper(I) through the sulfur atom only. These complexes are readily oxidised to the corresponding copper(II) complexes which contain a CuII-S(mercaptide) bond as demonstrated by the π(S)→CuII LMCT at 420 nm. The e.p.r. and electronic spectroscopic results are consistent with a distorted octahedral structure. Reactions of copper(I) with terpy and cysteine/ penicillamine in weakly acidic medium produce complexes containing two different copper(II) centres. From a strongly acidic medium, a binary copper(I) terpyridine complex is obtained instead and is shown from i.r. spectral absorptions to contain a protonated pyridyl ring.
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References
H. Sigel and D. B. McCormick,Acc. Chem. Res. 3, 201 (1970).
R. Griesser and H. Sigel,Inorg. Chem., 9, 1238 (1970).
H. Sigel, P. R. Huber, G. Griesser and B. Prij,Inorg. Chem., 12, 1198 (1973).
F. A. Walker, H. Sigel and D. B. McCormick,Inorg., 11, 2756 (1972).
W. L. Kwik and K. P. Ang,Aust. J. Chem., 31, 459 (1978).
W. L. Kwik, K. P. Ang and G. Chen,J. Inorg. Nucl. Chem., 42, 303 (1980).
W. L. Kwik and K. P. Ang,J. Chem. Soc., Dalton Trans., 452 (1981).
W. L. Kwik, K. P. Ang and P. C. Lau,J. Chem. Soc., Dalton Trans., 2269 (1983).
H. B. Gray, in R. F. Gould (Ed.),Bioinorganic Chemistry, American Chemical Society, Washington D.C., 1971, pp. 365.
J. Michael Downes, J. Whelan and B. Bosnich,Inorg. Chem., 20, 1081–1086 (1981).
K. Nakamoto,Infrared and Raman Spectra of Inorganic and Coordination Compounds, 3rd Edit., John Wiley, 1978.
P. A. Temussi and A. Vitagliano,J. Am. Chem. Soc., 97, 1572 (1975).
D. Matropaolo, J. A. Thick, J. A. Potenza and H. J. Schugar,J. Am. Chem. Soc., 96, 726 (1974).
J. L. Hughey, T. G. Fawcett, S. M. Rudich, R. A. Lalancetle, J. A. Potenza and H. J. Schugar,J. Am. Chem. Soc., 101, 2617 (1979).
G. Arena, R. P. Bonomi, E. Rizzarelli and A. Seminara,Inorg. Chim. Acta., 30, 13 (1978).
S. Chaberak and A. E. Martell,Organic Sequesting Agents, Wiley, New York, 1959.
J. A. Thich, D. Mastropaolo, J. Potenza and H. J. Schugar,J. Am. Chem. Soc., 96, 726 (1974),
P. L. Dedert, J. S. Thompson, J. A. Ibers and T. J. Marks,Inorg. Chem., 21, 969 (1982).
D. M. Adams,Metal-Ligand and Related Vibrations, Edward Ernold, London, 1968.
B. Hammond, F. H. Jardine and A. G. Vohra,J. Inorg. Nucl. Chem., 33, 1017 (1971).
V. Vortisch, P. Kroneck and P. Hemmerich,J. Am. Chem. Soc., 98, 282 (1976).
W. L. Kwik and K. P. Ang, unpublished results.
S. H. Laune, T. Lund and J. B. Raynor,J. Chem. Soc., Dalton Trans. 1389 (1975).
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Kwik, W.L., Ang, K.P. Mixed-ligand complex formation of (2,2′,2″-terpyridine)copper(I) and (2,2′2″-terpyridine)copper(II) with some sulfur-containing amino acids. Transition Met Chem 10, 50–54 (1985). https://doi.org/10.1007/BF00624204
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DOI: https://doi.org/10.1007/BF00624204