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Vaccination withanaplasma centrale: Response after an experimental challenge withanaplasma marginale

Vaccination AvecAnaplasma Centrale: Resultats Apres une Confrontation Experimentale AvecA. Marginale

Vacunacion ConAnaplasma Centrale: Respuesta Despues del Desafio Experimental ConAnaplasma Marginale

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Summary

The haematological and clinical responses to vaccination withAnaplasma centrale and to subsequent challenge withAnaplasma marginale were evaluated. Twenty Holstein steers 14 to 16 months of age were divided into two groups of 12 and eight animals respectively (groups I and II). Group I was inoculated on day zero with 107 A. centrale-infected erythrocytes and group II was kept as a control. On day 125 both groups were challenged with 5 × 107 A. marginale-infected erythrocytes.A. centrale inoculation produced low parasitaemias (maximum -x 2.7%), moderate packed cell volume (PCV) falls (minimum -x 20.5%) and no clinical symptoms. After the challenge group I had significantly lower parasitaemia (maximum -x 2.3%) and higher PCV (minimum -x 20.1%) than group II (7.5% and 14.5% respectively). Four steers from group II developed acute anaplasmosis and required treatment.

Résumé

Les auteurs ont évalué les résultats hématologiques et clinique de la vaccination avecAnaplasma centrale et secondairement ceux d'un essai comparatif expérimental avecAnaplasma marginale. Vingt bouvillons Holstein âgés de 14 à 16 mois ont été divisés en deux groupes (I et II) respectivement de 12 et 8 sujets. Le groupe I a reçu au jour J0 une injection de 107 érytrhocytes infectés parAnaplasma centrale. Le groupe II a servi de lot témoin. Au 125 ème jour les deux groupes ont été soumis à une injection de 5 × 107 érythrocytes infectés parAnaplasma marginale. L'injection d'A. centrale a produit une parasitémie légère (maximum -x 2,7 p.100), une chute modérèe du volume de l'Hématocrite (PVC) (minimum -x 20,5 p.100) et aucun symptôme clinique. Par rapport au groupe II et après l'épreuve expérimentale, le groupe I présentait significativement une parasitémie plus basse (maximum -x 2,3 p.100) et de taux plus élevés (minimum -x 20,1 p.100), contre 7,5 et 14,5 p.100 respectivement. Quatre bouvillons du groupe II ont été atteints d'une anaplasmose aigüe exigeant un traitement.

Resumen

Se evaluó la respuesta clínica y hematológica despues de la vacunación conA. centrale, seguida del desafío conA. marginale. Un grupo de novillos Holstein de 14 a 16 meses de edad, se dividieron en dos grupos de 12 y ocho animales respectivamente (grupos I y II). El grupo I se inoculó el día cero con 107 eritrocitos infectados conA. centrale, sirviendo el grupo II de testigo. El día 125, ambos grupos recibieron una descarga de 5 × 107 eritrocitos infectados conA. marginale. La inoculación conA. centrale produjo parasitémias bajas (máximo -x 2.7%), caídas moderadas del volumen corpuscular (PCV), (mínimo -x 20.5%) y no se presentaron síntomas clínicos, Despues de la descarga, el grupo I tuvo parasitémias significativamente más bajas (máximo -x 2.3%) y volumenes corpusculares (PCV) más altos (mínimo 20.1%) que el grupo II (7.5% y 14.5% respectivamente). Cuatro novillos del grupo II desarrollaron anaplasmosis aguda y fueron tratados.

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Anziani, O.S., Tarabla, H.D., Ford, C.A. et al. Vaccination withanaplasma centrale: Response after an experimental challenge withanaplasma marginale . Trop Anim Health Prod 19, 83–87 (1987). https://doi.org/10.1007/BF02297324

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