Abstract
Urinary angiotensinogen loss, transferrinuria and transferrin clearance, gamma G globulinuria and gamma G clearance, and the selectivity of proteinuria have been evaluated in 10 patients affected by proteinuric renal diseases. Urinary angiotensinogen concentration appeared to be very small in all cases (0.80±0.63 s.d. ng/ml). The absence of correlation between the urinary loss of angiotensinogen and the loss and the clearance of transferrin, side by side with the significant correlation between angiotensinogenuria and urinary loss and clearance of gamma G globulin, and the selectivity of proteinuria support the hypothesis that human angiotensinogen behaves like a high molecular weight protein.
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Favaro, S., Baggio, B., Castellani, A. et al. Urinary angiotensinogen loss in chronic proteinuric glomerulonephritis. International Urology and Nephrology 4, 195–198 (1972). https://doi.org/10.1007/BF02081843
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DOI: https://doi.org/10.1007/BF02081843