Abstract
The distribution half-life, elimination half-life, apparent volume of distribution and total body clearance of carbenicillin in healthy buffalo calves following a single intravenous administration (50 mg/kg) were 0.057±0.005 h, 1.688±0.11 h, 0.185±0.021 L kg-1 and 75.97±6.519 ml kg-1 h-1 respectively. A satisfactory dosage regimen for carbenicillin in buffalo calves was calculated to be 56 mg/kg followed by 52 mg/kg body weight repeated at 6 h intervals.
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Bal, M.S., Brar, K.S. The kinetic disposition and dosage regimen for carbenicillin in buffalo calves. Veterinary Research Communications 13, 389–394 (1989). https://doi.org/10.1007/BF00346071
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DOI: https://doi.org/10.1007/BF00346071