Abstract
Pulse-chase experiments show that, in addition to the secreted molecular forms of ceruloplasmin, an intracellular ceruloplasmin-like protein is synthesized in rat hepatocytes. Radioimmunochemical assay demonstrates that a nonserum isoform of ceruloplasmin is bound to the Golgi membranes.
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T. D. Aleinikova, V. B. Vasil'ev, N. K. Monakhov, and M. M. Shavlovskii,Biokhimiya,52, No 10, 1600–1607 (1987).
V. S. Gaitskhoki, O. V. Voronina, V. V. Denezhkina,et al.,,55, No 5, 927–937 (1990).
S. A. Neifakh, T. D. Aleinikova, V. S. Gaitskhoki,et al., Dokl. Akad. Nauk SSSR,224, No 1, 238–240 (1979).
L. V. Puchkova, V. V. Denezhkina, E. T. Zakharova,et al., Biokhimiya,55, No 11, 2111–2118 (1990).
B. Fleischer and S. Fleischer,Biochim. Biophys. Acta,219, No 2, 301–319 (1970).
E. Frieden, in:Biological Roles of Copper, Amsterdam (1980), pp. 93–113.
V. S. Gaitskhoki, V. M. L'vov, N. K. Monakhov,et al., Europ. J. Biochem.,115, No 1, 39–44 (1981).
V. Iyengar, G. J. Brewer, R. D. Dick, and C. Owyand,J. Lab. Clin. Med.,111, No 1, 267–274 (1988).
U. K. Laemmli,Nature,227, No 5259, 680–685 (1970).
I. A. Verbina, L. V. Puchkova, V. S. Gaitskhoki, and S. A. Neifakh,FEBS Lett.,292, No 2-3, 105–109 (1992).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 1, pp. 83–85, January, 1994
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Puchkova, L.V., Sasina, L.K., Aleinikova, T.D. et al. Intracellular ceruloplasmin-like protein of mammals. Bull Exp Biol Med 117, 86–88 (1994). https://doi.org/10.1007/BF02444089
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DOI: https://doi.org/10.1007/BF02444089