Summary
By means of the polarographic method a study was made of the dynamics of oxygen tension (pO2) in the brain tissues of dogs in prolonged overloads occurring during rotation in a centrifuge. As established, the rate of pO2 reduction is dependent on the magnitude, direction and period of acceleration. With an acceleration force of 2–12 g in the head-pelvis direction, pO2 dropped to 92–70% of the initial level after one minute of rotation, whereas in transverse overloads (back-chest) — to 98–80%. Overloads of 2–8 g in the pelvis-head direction caused a reduction of pO2 to 95–84%. The pO2 level in the brain tissues also depended on the position of the head in respect to the longitudinal axis of the animal body. But a moderate pO2 reduction in the brain tissue during rotation shows that hypoxia is not the only factor in the mechanism of disturbances caused by accelerations.
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Delivered at a meeting of the Moscow Society of Physiologists on March 9, 1962.
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Kovalenko, E.A., Popkov, V.L. & Chernyakov, I.N. In vivo study of the oxygen tension in the brain tissues during prolonged acceleration. Bull Exp Biol Med 55, 37–40 (1964). https://doi.org/10.1007/BF00800197
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DOI: https://doi.org/10.1007/BF00800197