Abstract
Alpha-fetoprotein (AFP) was detected by combined electrophoresis and precipitation in polyacrylamide gel (EPAG) in the sera of healthy blood donors. AFP was found in about half of the sera in concentrations of not more than 3 ng/ml. AFP could not be reliably determined in the other cases, the results being at the limit of sensitivity of the method. EPAG thus gives results fully comparable in sensitivity with the radioimmunological test and it fully retains the resolving power of double diffusion in gel. EPAG can be used to verify the specificity of the results of the radioimmunological test.
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Sokolenko, A.A., Abelev, G.I. Determination of background serum alpha-fetoprotein level in blood donors by combined electrophoresis and precipitation in polyacrylamide gel. Bull Exp Biol Med 81, 423–425 (1976). https://doi.org/10.1007/BF00804938
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DOI: https://doi.org/10.1007/BF00804938