Summary
A functional-anatomical brain scanner that has a temporal resolution of less than a hundred milliseconds is needed to measure the neural substrate of higher cognitive functions in healthy people and neurological and psychiatric patients. Electrophysiological techniques have the requisite temporal resolution but their potential spatial resolution has not been realized. Here we briefly review progress in increasing the spatial detail of scalp-recorded EEGs and in registering this functional information with anatomical models of a person's brain. We describe methods and systems for 124-channel EEGs and magnetic resonance image (MRI) modeling, and present first results of the integration of equivalent-dipole EEG models of somatosensory stimulation with 3-D MRI brain models.
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Acknowledgments: This work was supported by grants from agencies of the Federal government of the United States of America, including The National Institute of Neurological Diseases and Strokes, The National Institute of Mental Health, The Air Force Office of Scientific Research and The National Science Foundation. We gratefully acknowledge this support, as well as the efforts of our colleagues at the EEG Systems Laboratory, Drs. S. Bressler, B. Cutillo, and J. Illes, for their contributions to the research presented here.
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Gevins, A., Brickett, P., Costales, B. et al. Beyond topographic mapping: Towards functional-anatomical imaging with 124-channel EEGs and 3-D MRIs. Brain Topogr 3, 53–64 (1990). https://doi.org/10.1007/BF01128862
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DOI: https://doi.org/10.1007/BF01128862