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Halogenation of the components of nucleic acids

I. Bromine derivatives of the components of ribonucleic acid

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Chemistry of Natural Compounds Aims and scope

Summary

Preparative methods have been worked out for the bromination of unsubstituted AMP, GMP, UMP, CMP, and guanosine, and also methods for the isolation and purification of the bromine derivatives.

Some physicochemical characteristics (UV spectra, Rf values on thin-layer and paper chromatography, coefficients of millimolar extinction) of the bromine derivatives of the components of RNA obtained have been determined.

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Literature cited

  1. A. M. Michelson, J. Dondon, and M. Grunberg-Manago, Biochem. Biophys. Acta,55, 529 (1962).

    Article  CAS  PubMed  Google Scholar 

  2. M. Grunberg-Manago and A. M. Michelson, Biochim. Biophys. Acta,80, 431 (1964).

    CAS  PubMed  Google Scholar 

  3. M. Ikehara and S. Uesugi, Chem. Pharm. Bull. (Tokyo),17, 348 (1969).

    CAS  PubMed  Google Scholar 

  4. J. Filip and L. Bonacek, Radioisotopy,12, 949 (1971).

    CAS  Google Scholar 

  5. J. Filip, Radioisotopy,11, 203 (1970).

    Google Scholar 

  6. V. M. Vdovenko et al., Radiokhimiya,14, 457 (1972).

    CAS  Google Scholar 

  7. G. G. Gusev et al., in: The Production of Isotopes [in Russian], Moscow (1973), p. 165.

  8. I. F. Tupitsyn et al., in: The Production of Isotopes [in Russian], Moscow (1973), p. 158.

  9. N. S. Marchenkov, Author's Abstract of Candidate's Dissertation, Moscow (1974).

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Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 522–525, July–August, 1976.

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Mikhailov, K.S., Marchenkov, N.S., Chichikina, V.L. et al. Halogenation of the components of nucleic acids. Chem Nat Compd 12, 461–464 (1976). https://doi.org/10.1007/BF00564809

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  • DOI: https://doi.org/10.1007/BF00564809

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