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Synthesis and investigation of the biological activity of shortened analogues of luliberin

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Abstract

Five new luliberin analogues with shortened amino acid sequences have been synthesized. The different variants for obtaining the compounds under consideration are discussed. In an investigation of the biological activities of the analogues it was shown that they possess a pronounced action of the course of the ovulation processes in experimental animals.

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Scientific-Research Institute of Midwifery and Gynecology, USSR Academy of Medical Sciences, Leningrad. A. A. Zhdanov Leningrad State University. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 590–595, July–August, 1987.

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Burov, S.V., Nikolaev, S.V., Korkhov, V.V. et al. Synthesis and investigation of the biological activity of shortened analogues of luliberin. Chem Nat Compd 23, 496–499 (1987). https://doi.org/10.1007/BF00597814

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  • DOI: https://doi.org/10.1007/BF00597814

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