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Synthesis and investigation of the antitumoral activity of shortened analogs of luliberin

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Chemistry of Natural Compounds Aims and scope

Abstract

With the aim of obtaining antitumoral drugs possessing a binary action mechanism, we have synthesized a series of shortened analogs of luliberin, including some containing a 1-carboxymethyl-5-fluorouracil residue. Their antitumoral and hormonal activities have been investigated.

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Institute of High-Molecular-Mass Compounds, Russian Academy of Sciences, St. Petersburg. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 655–662, September–October, 1994.

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Semko, T.V., Burov, S.V., Veselkina, O.S. et al. Synthesis and investigation of the antitumoral activity of shortened analogs of luliberin. Chem Nat Compd 30, 607–612 (1994). https://doi.org/10.1007/BF00629874

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  • DOI: https://doi.org/10.1007/BF00629874

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