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The self-tuning controller: Comparison with human performance in the control of arterial pressure

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Abstract

A self-tuning controller was implemented for the automated infusion of sodium nitroprusside to lower mean arterial pressure in anesthetized dogs. The system incorporated a recursive least-squares parameter identifier and a modified minimumvariance controller. The onset delay was estimated on-line, the performance criterion included the cost of control, and requested step-changes were automatically translated into five successive smaller steps to reduce overshoot. The performance of the system in lowering mean arterial pressure was quantitatively compared with that of a well-trained anesthesiologist. In 10 runs in four animals, the automated system performed as well as the physician who devoted 100% of his attention to the task. Since the stability of the self-tuning controller cannot be guaranteed, such a system should be operated only in the presence of appropriate supervisory algorithms.

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Author notes

  1. Bruce K. Walker

    Present address: Department of Aeronautics and Astronautics, Massachusetts Institute of Technology, Massachusetts, USA

  2. P. S. Krishnaprasad

    Present address: the Electrical Engineering Department, University of Maryland, Maryland, USA

Authors and Affiliations

  1. Department of Biomedical Engineering, Case Western Reserve University, Wickenden 504, OH 44106, Cleveland, Ohio

    Kenneth S. Stern, Howard J. Chizeck, Bruce K. Walker, P. S. Krishnaprasad, Paul J. Dauchot & Peter G. Katona

  2. Department of systems Engineering, and Anesthesiology, Case Western Reserve University, Wickenden 504, OH 44106, Cleveland, Ohio

    Kenneth S. Stern, Howard J. Chizeck, Bruce K. Walker, P. S. Krishnaprasad, Paul J. Dauchot & Peter G. Katona

Authors
  1. Kenneth S. Stern
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  2. Howard J. Chizeck
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  3. Bruce K. Walker
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  4. P. S. Krishnaprasad
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  5. Paul J. Dauchot
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  6. Peter G. Katona
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Stern, K.S., Chizeck, H.J., Walker, B.K. et al. The self-tuning controller: Comparison with human performance in the control of arterial pressure. Ann Biomed Eng 13, 341–357 (1985). https://doi.org/10.1007/BF02407765

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