REFERENCES
Y. Takakura and M. Hashida. Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution. Pharm. Res. 13:820-831 (1996).
J. Kopecek and P. Rejmanova. Enzymatically degradable bonds in synthetic polymers. In S. D. Bruck (ed.), Controlled Drug Delivery, Vol. I, CRC Press, Boca Raton, 1983, pp. 81-124.
D. H. Lewis. Controlled release of bioactive agents from lactide/glycolide polymers. In M. Chasin and R. Langer (eds.), Biodegradable Polymers as Drug Delivery Systems, Marcel Dekker, New York, 1990, pp. 1-41.
F. A. Ferrari, C. Richardson, J. Chambers, S. C. Cauey, and T. J. Pollock. Patent application, international publication number W088/03533, 1986.
J. Cappello. Synthetically designed protein-polymer biomaterials. In K. Park (ed.), Controlled Drug Delivery: Challenges and Strategies, American Chemical Society, Washington D.C., 1997, pp. 439-453.
M. J. Fournier, S. H. Creel, M. T. Krejchi, T. L. Mason, and D. A. Tirrell. Genetic synthesis of periodic protein materials. Journal of Bioactive and Biocompatible Polymers 6:326-338 (1991).
D. W. Urry, C. M. Harris, C. X. Luan, C.-H. Luan, D. C. Gowda, T. M. Parker, S. Q. Peng, and J. Xu. Transductional protein-based polymers as new controlled-release vehicles. In K. Park (ed.), Controlled Drug Delivery: Challenges and Strategies, American Chemical Society, Washington D.C., 1997, pp. 405-437.
M. T. Krejchi, E. D. T. Atkins, A. J. Wadon, M. J. Fournier, T. L. Mason, and D. A. Tirrell. Chemical sequence control of β-sheet assembly in macromolecular crystals of periodic polypeptides. Science 265:1427-1432 (1994).
A. Wada, T. Shimayama, D.-M. Zhou, M. Warashina, M. Orita, T. Koguma, J. Ohkawa, and K. Raira. Ribozymes as antiviral agents. In K. Park (ed.), Controlled Drug Delivery: Challenges and Strategies, American Chemical Society, Washington D.C., 1997, pp. 357-385.
J. Cappello and F. Ferrari. Microbial production of structural protein polymers. In D. P. Mobley (ed.), Plastics from Microbes, Hanser Publishers, New York, 1994, pp. 35-92.
D. W. Urry, K. Okamoto, R. D. Harris, C. F. Hendrix, and M. M. Long. Synthetic, cross-linked polypentapeptide of tropoelastin: an anisotropic, fibrillar elastomer. Biochemistry 15:4083-4094 (1976).
J. Cappello, J. Crissman, M. Dorman, M. Mikolajczak, G. Textor, M. Marquet, and F. Ferrari. Genetic engineering of structural protein polymers. Biotechnol. Prog. 6:198-202 (1990).
J. Cappello. Application of genetically engineered protein polymers to drug delivery. Proceedings of the Eighth International Symposium on Recent Advances in Drug Delivery Systems. Salt Lake City, Utah, February 24–27, pp. 68-71, 1997.
D. W. Urry, D. T. McPherson, J. Xu, G. D. Channe, and T. M. Parker. Elastic and plastic protein-based polymers: potential for industrial uses. In D. P. Mobley (ed.), Plastics from Microbes, Hanser Publishers, New York, 1994, pp. 259-281.
D. W. Urry. Free energy transduction in polypeptides and proteins based on inverse temperature transitions. Prog. Biophys. Molec. Biol. 57:23-57 (1992).
J. Cappello, G. Textor, and B. Bauerle. Bioresorption of implanted protein polymer films controlled by adjustment of their silk/elastin block lengths. In G. G. Gebelien and C. E. Carraher (eds.), Industrial Biotechnological Polymers, Technomic Publishing Company, Lancaster, 1995, pp. 249-256.
A. J. Domb (ed.). Polymeric Site-Specific Pharmacotherapy, John Wiley & Sons, New York, 1994.
D. Putnam and J. Kopecek. Polymer conjugates with anticancer activity. Advances in Polymer Science 122:55-123 (1995).
I. Saiki, J. Iida, J. Murata, R. Ogawa, N. Nishi, K. Sugimura, S. Tokura, and I. Azuma. Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules. Can. Res. 49:3815-3822 (1989).
E. Yoshikawa, M. J. Fournier, T. L. Mason, and D. A. Tirrell. Genetically engineered fluoropolymers. Synthesis of repetitive polypeptides containing p-fluorophenylalanine residues. Macromolecules 27:5471-5475 (1994).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ghandehari, H., Cappello, J. Genetic Engineering of Protein-Based Polymers: Potential in Controlled Drug Delivery. Pharm Res 15, 813–815 (1998). https://doi.org/10.1023/A:1011999810298
Issue Date:
DOI: https://doi.org/10.1023/A:1011999810298