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Glucosebelastungen und Arginin-Infusionen bei Neugeborenen. Einfluß auf Wachstumshormon, Blutzucker, Fettsäuren und Glycerin

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Zusammenfassung

Glucoseinjektionen (0,33 g/kg Körpergewicht in 15 sec) und Arginin-Infusionen (0,5 g/kg Körpergewicht in 30 min) bei Neugeborenen verschiedenen Alters (1–2, 4 und 7 Tage) führten zum Anstieg des STH im Blut und zur Abnahme der freien Fettsäuren und des Glycerins. Die stärkste STH-Reaktion wurde bei den jüngsten Neugeborenen (1–2 Tage alt) beobachtet.

Summary

Glucose tolerance tests and arginine infusions were performed in 60 fullterm newborn infants at 1, 4, and 7 days of age. Glucose and arginine infusions were followed by an initial decrease of GH1 which was followed by an increase of GH levels exceeding base line values. Two hours after infusions GH levels were lower than in the beginning. The most pronounced changes of GH concentrations were observed in the youngest age group. FFA2 and glycerol levels initially decreased after glucose and arginine infusion.

It is suggested that GH plays an important role in protein synthesis and lipolysis particularly during the first days of life.

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Mit Unterstützung der Deutschen Forschungsgemeinschaft Stu 61/1 und Wo 69/7.

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Stubbe, P., Wolf, H., Stolte, G. et al. Glucosebelastungen und Arginin-Infusionen bei Neugeborenen. Einfluß auf Wachstumshormon, Blutzucker, Fettsäuren und Glycerin. Klin Wochenschr 48, 918–923 (1970). https://doi.org/10.1007/BF01487631

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  • DOI: https://doi.org/10.1007/BF01487631

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