Zusammenfassung
Die Reninaktivität im Plasma wurde bei Kaninchen im akuten Stadium der renalen Hypertonie bestimmt. Die Reninaktivität stieg bei der Hälfte der Tiere nach einseitiger Nierenarteriendrosselung an, während sie in den meisten Fällen nach beiderseitiger Nierenarteriendrosselung sowie nach Drosselung der Bauchaorta normal blieb. Zwischen Blutdruckverhalten und Reninaktivität im Plasma bestand keine Korrelation.
Summary
Plasma renin activity was measured in the acute stage of experimental renal hypertension in the rabbit. Plasma renin activity increased in half of the animals after unilateral constriction of renal artery, while it remained normal in almost all animals after bilateral constriction of renal arteries or after constriction of the abdominal aorta. There was no correlation between blood pressure and plasma renin activity.
Literatur
Blair-West, J. R., Coghlan, J. P., Denton, D. A., Orchard, E., Scoggins, B. A., Wright, R. D.: Renin-angiotensin-aldosterone system and sodium balance in experimental renal hypertension. Endocrinology83, 1199 (1968).
Brown, T. C., Davis, J. O., Olichney, M. J., Johnston, C. I.: Relation of plasma renin to sodium balance and arterial pressure in experimental renal hypertension. Circulat. Res.18, 475 (1966).
Fasciolo, J. C., Vito, E. de, Romero, J. C., Cucchi, J. N.: The renin content of the blood of human and dogs under several conditions. Canad. med. Ass. J.90, 206 (1964).
Fujii, J., Kurihara, H., Yamaguchi, H., Ikeda, M.: Saltrich diet and experimental renovascular hypertension in the rabbit. Tohoku J. exp. Med.97, 191 (1969).
Lever, A. F., Robertson, J. I. S.: Renin in the plasma of normal and hypertensive rabbits. J. Physiol. (Lond.)170, 212 (1964).
Mogil, R. A., Itskovitz, H. D., Rusel, J. H., Murphy, J. J.: Renal innervation and renin activity in salt metabolism and hypertension. Amer. J. Physiol.216, 693 (1969).
Pickens, P. T., Bumpus, F. M., Lloyd, A. M., Smeby, R. R., Page, I. H.: Measurement of renin activity in human plasma. Circulat. Res.17, 438 (1965).
Regoli, D., Hess, R., Brunner, H., Peters, G., Gross, F.: Interrelationship of renin content in kidney and blood pressure in renal hypertensive rats. Arch. int. Pharmacodyn.140, 416 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fujii, J., Seki, A., Yamaguchi, H. et al. Reninaktivität im Plasma im akuten Stadium der experimentellen renalen Hypertonie. Klin Wochenschr 48, 1128–1129 (1970). https://doi.org/10.1007/BF01496405
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01496405