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Untersuchungen über die Aktivität des sympathischen Nervensystems und der Nebennierenrinde während akuter respiratorischer Acidose

Studies on the activity of the sympathetic nervous system and the adrenal cland cortex during acute respiratory acidosis

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Summary

The impact of experimentally induced acute respiratory acidosis on the activity of the sympathetic nervous system was studied in young healthy subjects. — Acute respiratory acidosis produces a significant increase in the concentration of plasma free fatty acids and in urinary excretion of catecholamines in healthy subjects. These results support the hypothesis that acute respiratory acidosis causes an increase in the activity of the sympathetic nervous system. No enhanced liberation of adrenal steroids was observed during acute hypercapnia.

Zusammenfassung

Eine experimentell induzierte akute, respiratorische Acidose wird von gesunden Versuchspersonen mit einem signifikanten Anstieg der freien Fettsäuren im Plasma und einer Zunahme der Katecholaminausscheidung im Harn beantwortet.

Diese Befunde sprechen dafür, daß eine akute respiratorische Acidose beim Gesunden zu einer nicht unbeträchtlichen Aktivierung des sympathischen Nervensystems führt.

Eine vermehrte Freisetzung von Nebennierenrindensteroiden während akuter Hyperkapnie war nicht nachweisbar.

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Authors and Affiliations

  1. Medizinische Kliniken und Polikliniken der Justus Liebig-Universität Gießen, Germany

    L. Geisler, H. -D. Rost & H. J. Dengler

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  1. L. Geisler
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  2. H. -D. Rost
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  3. H. J. Dengler
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Geisler, L., Rost, H.D. & Dengler, H.J. Untersuchungen über die Aktivität des sympathischen Nervensystems und der Nebennierenrinde während akuter respiratorischer Acidose. Klin Wochenschr 49, 87–91 (1971). https://doi.org/10.1007/BF01497305

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