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Mycoplasma interactions with cell cultures, uncultured living cells and the problems posed by their presence in tissue cultures

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Summary

The presence of mycoplasmas in tissue cultures has created many problems for investigators employing cell cultures, especially with respect to the interpretation of the results. It was partly because of these problems encountered in mycoplasma-infected tissue cultures that increased attention was paid to this group of organisms and many unique interactions of these organisms with cell cultures, uncultured living cells and viruses were discovered, which have been reviewed in the present paper.

Zusammenfassung

Für die Forscher, die die Methodologie der Zellkulturen in bezug auf die Deutung ihrer Ergebnisse benutzen, rufen Mycoplasmen, durch ihre häufige Gegenwart in Zellkulturen viele Probleme hervor. In der übersicht werden besprochen die Wirkungen auf den Zellstoffwechsel, auf Chromosomen, Transformationen in maligne Zellen, Anheftung an und Wechselwirkung mit der Zellmembran, intracelluläre Existenz. Beziehungen von Mycoplasmen und Viren, nachgewiesene Mycoplasmen-Arten in Zellkulturen und Methoden zu ihrer Feststellung.

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    K. K. Sethi & M. Teschner

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Sethi, K.K., Teschner, M. Mycoplasma interactions with cell cultures, uncultured living cells and the problems posed by their presence in tissue cultures. Klin Wochenschr 50, 226–233 (1972). https://doi.org/10.1007/BF01486526

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